When it comes to acne - the world's most common skin issue - the struggle is beyond real. Dealing with this relentless beast affects not only your skin, but it can also play some real nasty tricks on your mental health, kicking anxiety, depression, and self-esteem issues into high gear.

That's where over-the-counter (OTC) acne treatments can come in handy, acting as an easily accessible first line of defense against those pesky pimples. These solutions range widely - lotions, creams, gels, scrubs, and cleansers galore.

Let's get to know some of the top-hit-listers you'll find hanging out on the pharmacy shelves:

• Benzoyl peroxide, the long-standing bad-boy of acne treatment you've probably heard of.
• Salicylic acid, or as we like to call it, the chemical peel wizard.
• Alpha hydroxy acids (AHAs) - that's fancy talk for goodies like glycolic, citric, lactic, and malic acid.
• Sulfur - not commonly used these days, but still pops in to say 'hi' sometimes.
• Tea tree oil doesn't just pack a punch against acne; it's also great for bug bites and fungal infections.
• Retinoids, or vitamin A derivatives and rockstars of moderate acne treatment.
• Azelaic acid, naturally found in barley and grains and plays no games with acne-causing bacteria.
• Witch hazel, reducing inflammation one drop at a time.

So you've got your options, now what? Take a hard look at them: consider aspects like your skin type, the kind of acne at play, and quite frankly, whether you find that lemon-grass scent refreshing or repulsive.

Remember: using these products correctly is critical. Don't go all mad scientist mixing ingredients unless advised by a health professional. And keep in mind OTC solutions are a starting point. If they're not working or messing with your mental health, reach out to a healthcare provider, stat!

Managing acne is a trial-and-error journey. Be patient, stay consistent, and do not hesitate to seek professional help when needed. After all, you're not just taking care of your skin, but your overall well-being too.