Turns out, the wild party your stomach throws when downing a chili cheese dog or enjoying a late-night burrito binge might be having a ripple effect on other parts of your body. The bouncer at this party? Proton pump inhibitors (Hereon known as “PPI” because who has time for a term that's nine syllables long?), heartburn medication that promises to settle the dawn-breaking brunch revolt happening in your gut.

However, a recent study suggests that these very PPIs, lauded as the saviors of esophageal peace, might be inviting another unwanted guest to the shindig – an earth-shaking headache.

Say what? Yep, you didn’t read it wrong. The party doesn’t end in the stomach. It moves north, bringing along the most unwelcome gift – migraines. Margaret Slavin, PhD, the queen of migraine-food-nutrition at the University of Maryland, linked the use of PPIs with an increased risk of having migraines. So, the meds that were supposed to quell your epicurean rebellion may actually be backfiring.

In case you were wondering about the numbers, those who use PPIs, containing hip names like 'Prevacid', 'Prilosec', or 'Nexium', are 70% more likely to experience migraine attacks or severe headaches than those who didn’t. Looks like PPIs have more baggage than a transatlantic flight.

However, don't flush your pills just yet. Slavin and her science squad caution that these results don’t establish a direct cause-and-effect relationship, simply an association. Notably, those with migraines are known to have upticks in GI conditions to begin with, and certain pain medications (yes, we're looking at you, caffeine and ibuprofen) are notorious for causing an upset tummy that could necessitate more use of acid-suppressing meds. But we’re not just pointing fingers at PPIs. In this blame game, H2 blockers and common antacids like 'Tums' and ‘Alka-Seltzer’ are getting a piece of the action too.

While acid suppressing drugs have their crucial place in managing acid reflux or serious conditions like ulcers and esophageal cancer, if you're a migraine sufferer, it might be worth having a good old heart-to-heart with your friendly neighborhood Doctor. Have we found the ugly stepchild of acid reflux medication? Only time will tell. Meanwhile, proceed with caution, your beloved antacid might just be giving you that nasty headache after all.